081822---Dr.-Sears-Answers-Protein-Powder-blog

Dr. Sears Answers Your Questions On Protein and Protein Powder

The global market for protein supplements is anticipated to rise 8.5% by 2030. This increased demand is widely due health-conscious individuals, fitness go-ers, and millennials looking to add more balance to their diets. In this blog, Dr. Sears covers some basic questions on protein and then gets into protein powders and what you need to know.

Q. How much protein do you need each day?

A. It depends on your lean body mass and your level of physical activity. The reason you need protein is to maintain and repair damaged muscle tissue. If you are an active athlete, you will have more muscle mass, and your training will damage your existing muscle. Therefore, these individuals are going to need more protein. On the other hand, the average American male needs about 110 grams of protein per day, and the average American female requires about 90 grams per day. That amount of protein should be spread out throughout the day. This means you should eat no more protein at a meal than can fit on the palm of your hand. That’s about 3 ounces of protein for a female and 4 ounces for a male.

Q. What are the primary nutritional differences between animal protein versus plant protein?

A. Of the 20 amino acids in any protein source, only nine are essential. This designation is because essential amino acids can’t be synthesized by the body and must be supplied by the diet. Animal protein has a complete range of amino acids, whereas plant protein is usually deficient in some essential amino acids. 

Q. Does protein build muscle mass?

A. To help with muscle growth, you need adequate protein in the diet and weight-bearing exercise.Simply consuming more protein doesn’t build muscle. Exercise causes muscle damage and this stimulates new muscle formation to replace the muscle that has been damaged. The higher the intensity of exercise, the more protein you need.

Q. Does protein increase satiety?

A. A benefit of adequate protein consumption is that it increases satiety. It does this by releasing hormones from the gut that go directly to the brain to stop hunger and by increasing the release of the hormone glucagon from the pancreas to stabilize blood sugar levels. This lack of appetite is why you want to consume adequate protein at every meal, especially breakfast.

Q. Can you consume too much protein?

A. The answer is yes. Of the nine essential amino acids, three are branched-chain amino acids. These amino acids are leucine, isoleucine, and valine, and these have the most significant effect on stimulating muscle development by activating the gene transcription factor called mTOR. High levels of mTOR are associated with insulin resistance, eventually leading to many chronic diseases such as diabetes and cancer.

Q. Is there a connection between mTOR and AMPK?

A. The more you activate mTOR, the more you inhibit your master regulator of metabolism known as AMPK. Low levels of AMPK activity ultimately cause insulin resistance. As a result, you want to keep your protein consumption in a zone; not too high but not too low. With this as a background, let’s talk about using protein powder to ensure you get enough protein to maintain your muscle mass but not too much to inhibit AMPK.

Q. What are the benefits of using protein powder?

A. Many of our meals, especially breakfast, can fall short on protein. If you are over the age of 50, you are likely not getting enough protein in your day. Protein is vital as we age since older adults are prone to losing muscle mass, resulting in loss of strength and function. Protein powder can help fill in the gaps when intake falls short. Isolated protein powder can also help balance out excess carbohydrate intake to provide a better hormonal response at meals generating stable blood sugar levels and hence greater satiety between meals.

Q. Can protein powder help with weight management?

A. It can as it helps to create satiety and minimize cravings.  

Q. How should protein powder be used?

A. It should be used as an additive to carbohydrate-rich meals. For example, adding protein powder to oatmeal provides a superior meal compared to oatmeal alone, or adding protein power to a fruit smoothie will give excellent appetite suppression.

Q. Can you use protein powder daily and is there a better time of day to use it?

A. Yes, you can use protein powder daily as long as you don't exceed your daily protein requirements. Breakfast is probably the best meal to use it since that meal is most likely to contain excess carbohydrates relative to protein. 

Q. Who should use protein powder? 

A. Anyone who does not feel they are getting enough protein in a meal.

Q. How do you know if it’s right for you or working?

A. Your best indicator is the increasing lack of hunger after a meal.

Q. Are there any negatives to using protein powder? 

The key with protein powder is making sure you do not consume too much relative to the rest of your meal. I generally tell people to aim for a total of 25 grams of protein at each meal and about 7-14 grams at each snack. This takes into account all of the sources of protein at each meal and a good gauge to know how much to consume. You do want to pay attention to the quality of the amino acids in the protein powder you choose. Some sources such as collagen are very poor in essential amino acids and therefore would not be recommended.

Q. What type of protein powder is best, and what ingredients should you look for?

A. I think dairy protein powders are best, but recommend looking for ones that are lactose-free. Plant-based protein sources such a soy or pea don't have the taste of dairy-based protein powders, but can be used for those who avoid dairy. All protein powders are superior to collagen protein which is highly deficient in essential amino acids.

 


 

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022724---Weight-Loss-Blog

Dr. Sears Q&A: Weight Loss

With so much interest in weight loss and so much buzz around weight loss drugs, we put together some of the top questions we get in this latest Q&A blog. Here Dr. Sears answers your questions on weight loss, weight loss drugs and what he thinks is the most scientifically backed way to lose weight. See what he has to say.Question: What medical conditions could impede weight loss, and how can they be identified?  Answer:  Any condition associated with insulin resistance will make it difficult to lose weight.  This would include diabetes, heart disease, neurological disease, etc.  Also, any drug that induces insulin resistance will also make it difficult to lose weight.  These include corticosteroids and many neurological drugs. Question: How do hormones affect weight loss, and which imbalances are most detrimental? Answer: High levels of insulin (caused by insulin resistance), high levels of cortisol (caused by stress), and low levels of satiety hormones such as GLP-1 will make weight loss difficult. Question: Is there a connection between sleep quality and weight loss? Answer: Poor quality sleep increases cortisol levels that lead to insulin resistance. The higher your level of insulin resistance, the more difficult it is for any organ to remove glucose from the blood for transport into the cell, where it can be converted to energy. This i Question: Do any weight loss supplements work?  Answer: Not really. You have to restrict calories to activate AMPK which causes your body to effectively burn excess stored body fat.   Question: What medications are FDA approved for weight loss? Answer: There are number of approved older drugs, but the most widely used is still an old drug (Phentermine) that was only recently approved for long-term use. However, the new injectable GLP-1 receptor agonists are more powerful and more popular. The scientific name for the most well-known injectable weight-loss drug is semaglutide, which is marketed under the tradenames Ozempic and Wegovy. In simple terms, these injectable drugs activate the release of the hormone GLP-1 from the gut that goes directly to the brain to tell you to stop eating. These drugs were initially developed to treat type 2 diabetes, but the clinical studies in overweight and obese individuals demonstrated significant weight loss at higher levels. Question: What are the unintended side effects of weight loss medications (i.e. GLP-1s, dual GIP/GLP-1). Answer: One major problem is that the lack of hunger caused by the drug makes you less likely to consume sufficient protein to maintain lean body mass.  Lean body mass is defined as functional tissue such as organs (including the brain) and bone.  Nearly 40 percent of the weight loss in obese patients comes from loss of lean body mass.  Without adequate protein (especially on a diet that is calorie-restricted because of lack of hunger), the replacement of damaged cells is compromised.  The skin and hair are the first site to suffer.  This lack of protein also makes it difficult to maintain mitochondrial function that provides energy for each of your 30 trillion cells. As a result, fatigue (both mental and physical) is often experienced. Question: Would you recommend an injectable weight loss drug? Answer: The answer is no. There is a big difference between weight loss and fat loss. Weight loss is the combined loss of stored body fat and lean body mass (i.e., muscle). You want to lose fat but not muscle. Although the weight loss using weekly semaglutide injections is impressive according to the literature, a deeper look shows that about 40 percent of that weight loss is due to loss of lean body mass. That is not a good sign. It suggests that the injections reduce hunger to the extent that the person has little desire to eat enough protein to maintain muscle mass. In essence, the drug increases the patients' sarcopenia (muscle loss). One of the consequences of sarcopenia is increased frailty. Also once you stop using these weight loss drugs, the weight quickly returns. Question: Does a high protein diet help with weight loss? Answer: Most high protein diets are ketogenic diets that disrupt metabolism in addition to being high fat.  The appropriate diet is protein-adequate (about 30 grams of protein at each meal), carbohydrate-moderate (primarily non-starchy vegetables, low-fat (to reduce calories) and rich in fermentable fiber.  The common name for such a diet is the Zone diet. The ideal amount of protein at each meal for weight loss is about 30 grams. Less than 30 grams of protein at meal will not generate the hormonal signals from the gut to stop hunger. Too much protein at meal, greater than 30 grams, will inhibit AMPK activity which helps cells burn excess stored fat.  

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020524-Winter-E-Newsletter-Blog-4

Aging: Can You Slow It Down?

The first few weeks of the New Year are often focused on the resolve to lose weight, when in actuality people should focus their goals on slowing down aging, no matter the time of year. The only regimen that clinically achieves results in slowing the aging process is calorie restriction without malnutrition. Why? It’s not simply losing weight but orchestrating the complex interplay of reducing senescent cells, reprograming your metabolism, and changing gene expression, leading to a longer and better life.   A Timeline of Calorie Restriction   The first recorded human experiments with calorie restriction began with the written books of Luigi Cornaro in the 16th century, as I outlined in my book The Anti-Aging Zone, published in 1999. However, the molecular mechanisms of why calorie restriction is so effective required more recent breakthroughs in metabolism and epigenetics that were confirmed with the CALERIE study that carefully controlled the diets of 225 participants over two years and then ongoing testing of their retained blood samples.     The results of the CALERIE study have been impressive. However, the one clear take-home lesson was that reduction of insulin resistance was the most predictive blood marker correlated with the genetic changes and the decrease in senescent cells that ultimately accelerate aging.   The Zone on Calorie Restriction   The Zone diet is a calorie-restricted diet that was patented to reduce insulin resistance. It requires balancing macronutrients at each meal to generate the rapid hormonal changes that give rise to satiety. Only then can you follow calorie restriction for a lifetime without hunger and fatigue. It starts with having enough protein at each meal to create satiety in the brain's appetite control center. You need about 30 grams of protein (no more, but no less) at each meal to generate the same hormonal responses induced by the recent injectable weight loss drugs. However, you also must balance that protein with an adequate level of low-glycemic carbohydrates (about 40 grams) to stabilize blood glucose levels, and then add a dash of monounsaturated fat (about 15 grams). Over the years, it has been demonstrated by more than 40 research publications that the Zone diet is superior to ketogenic diets and the Mediterranean diet under controlled clinical research.    A New Technology to Slow Down Aging  Unfortunately, many people think the Zone diet requires too much thinking.  That’s why I developed Zone Foods to overcome that problem. The first generation of Zone Foods demonstrated dramatic reductions in insulin resistance compared to a control group, getting an equal number of calories (1). The second generation of Zone Foods offers greater variety and even more appetite suppression without thinking. This second generation will include new and improved versions of the Zone Pasta and Zone Bars, with new additions of Zone Muffins, Zone Oatmeal, Zone Granola, Zone Soups, and Zone Cookies (coming soon!). Each Zone Food contains 15 grams of protein, balanced with the appropriate level of low-glycemic carbohydrates, so any combination of two Zone Foods will provide the critical 30 grams of protein at a meal to stop hunger and maintain peak mental awareness for the next five hours. The growing variety of Zone Foods makes following the Zone diet incredibly easy. If you are never hungry, that indicates that you are reducing insulin resistance. The long-term benefit to you is slowing aging, which is only possible with lifelong use of Metabolic Engineering that starts with the Zone diet as its foundation. You May Also Like: Reaching the Zone Using Metabolic Engineering

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